Indianapolis Colts linebacker Tyjuan Hagler has been placed on injured reserve with a ruptured biceps, coach Jim Caldwell announced today. Hagler suffered the season-ending injury Sunday against San Francisco.

Philip Wheeler or Ramon Humber will replace him and start on Sunday against Houston at Lucas Oil Stadium. Wheeler was a third-round draft pick in 2008.

Humber is an undrafted rookie from North Dakota State.

Neither has started a game.

Wheeler had the strong-side linebacker job during the preseason but was beat out by Hagler. Whether Wheeler is ready this time can’t be a question.

“He has to be,” Caldwell said.

Caldwell also said he expected cornerback Marlin Jackson to return to practice today after missing the past three games with a knee injury and said wide receiver Reggie Wayne did not aggravate the groin injury with which he played against San Francisco.

The coach didn’t expect cornerback Kelvin Hayden (knee) or wide receiver Anthony Gonzalez (knee) to practice but offered no timetable for their return.